Healthcare is evolving quickly, and 2025 was no exception. From the rise of generative AI in clinical decision-making to surprising discoveries about neurodegenerative diseases, this year’s top Health Notes articles reflect the curiosity, innovation, and commitment that drive our community forward. These stories don’t just inform; they inspire conversations about the future of medicine, patient care, and the role of technology in improving outcomes.
As we step into the new year, let’s revisit some of the articles in 2025 that captured your attention and sparked meaningful dialogue across the healthcare landscape.
Top Health Notes Articles by Pageview
These Health Notes articles drew the largest audiences, offering insights into emerging trends and critical clinical topics:
1. EBSCO’s Clinical Decisions Releases Editorial Approach to Generative Artificial Intelligence
Generative AI has been one of the most talked-about technologies in healthcare this year. EBSCO’s Clinical Decisions shared its editorial principles for integrating AI into point-of-care resources, emphasizing a measured, evidence-based approach to ensure trust and accuracy.
2. Five Things I’ve Learned as a Physician Building Dyna AI
Dr. Kate Eisenberg, MD, PhD, FAAFP, Senior Medical Director for DynaMed Decisions, offered a behind-the-scenes look at building Dyna AI. Her reflections on innovation, collaboration, and clinical integrity resonated with readers eager to understand the future of AI in medicine.
3. “Outbreak” of ALS in the Alps Stumps Researchers
A mysterious cluster of amyotrophic lateral sclerosis (ALS) cases in a French ski town led researchers to investigate environmental factors. Could a local mushroom hold clues to this devastating disease? This article combined intrigue with scientific rigor, making it one of the year’s most compelling reads.
4. Initiating Insulin in Patients with Type 1 Diabetes
Managing type 1 diabetes remains a cornerstone of endocrinology. This practical guide on initiating insulin therapy – a top Health Notes article three years in a row – reinforced best practices for clinicians and underscored the importance of specialist involvement.
5. EBM Focus: 127 Patients With COVID Took Paxlovid and You Won’t Believe What Happened Next…
The headline grabbed attention, but the content delivered nuanced insights: while viral rebound after Paxlovid may not harm individual patients, its implications for public health and transmission risk remain substantial.
Top Health Notes Articles by Engagement Rate
These Health Notes articles sparked conversation and deeper engagement among readers:
1. Five Things You Might Not Know About Health Care for Veterans
Army veteran and DynaMed Deputy Editor Dr. Dan Randall shared key considerations for caring for veterans outside the VA system—a topic that resonated with clinicians committed to comprehensive care.
2. Management of Avoidant/Restrictive Food Intake Disorder (ARFID)
Part of a two-part series, this article shed light on a complex eating disorder often misunderstood in clinical practice, offering practical guidance for diagnosis and management.
3. EBM Focus: The Dupilumab Dilemma – Trading Eczema for Psoriasis?
A JAMA Dermatology study raised questions about dupilumab’s safety profile. Our EBM Focus team explored whether the risk of psoriasis should change prescribing practices.
4. EBM Focus: Stimulants Save Lives – The Unspoken Harms of Untreated ADHD
This Health Notes article highlighted a striking finding: initiating stimulants for attention deficit hyperactivity disorder (ADHD) significantly reduced mortality, underscoring the importance of timely diagnosis and treatment.
5. The Next Era of Disease Detectives: Parkinson Disease Sniffing Dogs
Could dogs revolutionize early detection of Parkinson disease? This fascinating article explored the science behind scent-based diagnostics and its potential to transform care.
Looking Ahead to Health Notes in 2026
From AI-driven clinical tools to unexpected breakthroughs in disease research, 2025 reminded us that as healthcare innovation is accelerating, clinicians need trusted, evidence-based resources to keep pace. Thank you for joining us on this journey. Here’s to another year of learning, discovery, and improving patient care.
